• Prevent scratching or rubbing whenever possible.

• Protect skin from excessive moisture, irritants, and rough clothing.

• Maintain a cool, stable temperature and consistent humidity levels.

• Limit exposure to dust, cigarette smoke, pollens, and animal dander.

• Recognize and limit emotional stress.

In allergic diseases, IgE antibodies are produced in response to different allergens. When an allergen comes into contact with IgE on specialized immune cells, the cells release various chemicals, including histamine. These chemicals cause the symptoms of an allergic reaction, such as wheezing, sneezing, runny eyes, and itching. The release of histamine and other chemicals alone cannot explain the typical long-term symptoms of the disease. Research is underway to identify factors that may explain why too much IgE is produced and how it plays a role in the disease.